A fault location method for transmission line based on the weighting of reliability is proposed. First, reactance component is used to reduce the influence of transition resistance on single-ended impedance location algorithm. Second, using single-ended impedance location algorithm to determine the approximate range of the reflected traveling wave′s arrival time and solving the problem that single-ended traveling wave location algorithm can not accurately locate the fault in the second half of the line. Third, evaluating the reliability of single-ended impedance location algorithm, double-ended impedance location algorithm, single-ended traveling wave location algorithm and double-ended traveling wave location algorithm. The reliability evaluation criteria includes channel state, transition resistance, fault location and so on. Finally, the final fault location result is obtained based on the weighting of reliability. The simulation results show that the proposed fault location method has strong robustness and high accurate. It will not be affected by the factors such as fault type and line channel status.